1912年（民國元年），北洋醫學堂改稱“直隸公立醫學專門學校”。
1915年（民國四年），學校由天津遷往保定。
1921年（民國十年），直隸省在保定成立河北大學，直隸公立醫學專門學校改稱“河北大學醫科”。
1932年1月，河北大學解散，醫科獨立建院，稱“河北省立醫學院”。
1937年，“七七事變”后學校被迫停辦。
1946年1月，學校奉令復員。
In 1912, Beiyang Medical School was renamed as “Zhili Public Specialized Training College in Medicine”.
In 1915, the College was relocated to Tianjin from Baoding.
In 1921, Hebei University was founded in Baoding with the approval of Zhili Province. Zhili Public Specialized Training College in Medicine was renamed as “Hebei University Medical School”.
In January 1932, Hebei University was dissolved. Hebei University Medical School became independent and was renamed as “Hebei Provincial Medical College”.
In 1937, Hebei Provincial Medical College was forced to suspend teaching after “Marco Polo Bridge Incident”.
On January 1946, the College was commanded to resume.
